Letter 105: Why John called the Jews generations of vipers.
Isidore of Pelusium→Eutonios|c. 392 AD|Isidore of Pelusium|Human translated
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John called the Jews "offspring of vipers," as wicked progeny of wicked parents. For they say this beast devours its mother's womb in being born. Since, then, the Jews abandoned the God who begat them, and turned against the very one who fashioned them, they rightly received the name of those creatures that destroy the source of their own life.
Why John called the Jews generations of vipers[6]. John called the Jews “generations of vipers” as being more wicked than the offspring of wicked parents. For it is recounted that this wild species[7] devours the maternal womb when they are hatched. Since then they abandoned God who gave them birth and they mortified all the grace given to them through failing to make use of it, he quite reasonably likens them to those poisonous creatures, who negate their benefactions through ingratitude, or to put it otherwise devour them.
John called the Jews "offspring of vipers," as wicked progeny of wicked parents. For they say this beast devours its mother's womb in being born. Since, then, the Jews abandoned the God who begat them, and turned against the very one who fashioned them, they rightly received the name of those creatures that destroy the source of their own life.
Human translation - Roger Pearse (additional translations)